| 免疫应答异常在克山病发病中的作用 |
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| 引用本文： | 吴振荣,钟学宽.免疫应答异常在克山病发病中的作用[J].中国地方病学杂志,1991,10(5):275-277. |
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| 作者姓名： | 吴振荣 钟学宽 |
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| 作者单位： | 中国地方病防治研究中心克山病研究所
(吴振荣，钟学宽，武常莉，许永丽，周令望，董显辉)，中国地方病防治研究中心克山病研究所(夏德义) |
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| 摘 要： | 本文报道了69例慢型和潜在型克山病患者的免疫应答。结果表明慢型克山病惠者 T细胞亚群,总 T 细胞(T_3)和抑制性 T 细胞(Ts)百分率明显下降,Th/Ts 比值显著升高。慢克患者的血清 IgG、循环免疫复合物(CIC)和心脏反应性抗体(HRA)阳性率比对照组明显上升,血清 C_3水平下降。红细胞免疫粘附功能慢克也明显低下。本文对上述结果的临床意义进行了讨论。
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| 关 键 词： | T细胞亚群 循环免疫复合物 心脏反应性抗体 红细胞免疫粘附功能 克山病 |
Imba lance of immune response in pathogenesis of Keshan disease |
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| Wu Zhenrong,et al.Imba lance of immune response in pathogenesis of Keshan disease[J].Chinese Jouranl of Endemiology,1991,10(5):275-277. |
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| Authors: | Wu Zhenrong |
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| Abstract: | Immunologic status of 69 cases with chronic and latent Keshan disease was studied.It was found that T cell subpopulation(T_3,Ts)percentage was apparen-tly decreased in patients with chronic Keshan disease,while the rate of T_h/T_sremarkably increased.IgG,CIC levels and positive rate of HRA from the seraof above patients were higher than that in control(P<0.01).C_3 levels of the sera was reduced.A significant reducing of red cell immunological adherentfunction in patients with chronic Keshan disease was also found.The clinicalsignificance of these rusults were discussed. |
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| Keywords: | T cell subpopulatin CIC HRA Red cell immunological adherent function Keshan disease |
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