| 注射用阿莫西林钠克拉维酸钾与氯化钠注射液配伍稳定性考察 |
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| 引用本文： | 张靖贤,林自中,黄鲜娇.注射用阿莫西林钠克拉维酸钾与氯化钠注射液配伍稳定性考察[J].中国药房,2003,14(12):750-751. |
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| 作者姓名： | 张靖贤 林自中 黄鲜娇 |
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| 作者单位： | 广西医科大学附属第一医院药剂科,南宁市,530021 |
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| 摘 要： | 目的 :为临床合理用药提供科学依据。方法 :选择5℃、25℃、37℃在3h内观察配伍液的外观、pH值 ,用高效液相色谱法测定阿莫西林钠与克拉维酸钾的含量。结果 :其稳定性与温度、日光有关。结论 :配伍液不稳定 ,日光照射及高温时不宜放置过久
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| 关 键 词： | 注射用阿莫西林钠克拉维酸钾 氯化钠注射液 配伍 稳定性 |
| 文章编号： | 1001-0408(2003)12-0750-02 |
| 修稿时间： | 2003年3月26日 |
Study on the Stability of Amoxicillin Sodium and Clavulanate Potassium for Injection in Sodium Chloride Injection Solution |
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| ZHANG Jingxian,LIN Zizhong,HUANG Xianjiao.Study on the Stability of Amoxicillin Sodium and Clavulanate Potassium for Injection in Sodium Chloride Injection Solution[J].China Pharmacy,2003,14(12):750-751. |
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| Authors: | ZHANG Jingxian LIN Zizhong HUANG Xianjiao |
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| Abstract: | OBJECTIVE:To study the stability of amoxicillin sodium and clavulanate potassium for injection in sodium chloride injection solution so as to offer a scientific basis for rational use of drug in clinical practice.METHODS:The external appearance and pH values of the mixed solution were observed,and the contents of Amoxicillin sodium and Clavulanate potasˉsium were determined by HPLC method at5℃,25℃and37℃within3hours.RESULTS:The stability was related to the temperature and sunlight.CONCLUSION:The mixed solution is instable and should not be put in storage for long time. |
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| Keywords: | Amoxicillin sodium and Clavulanate potassium for injection sodium chloride injection compatibility stability |
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