| 肺部细菌感染患者血清降钙素原水平变化及临床意义 |
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| 引用本文： | 吴兴萍. 肺部细菌感染患者血清降钙素原水平变化及临床意义[J]. 中国医药指南, 2011, 9(23): 36-37 |
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| 作者姓名： | 吴兴萍 |
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| 作者单位： | 连云港市第一人民医院呼吸内科,江苏,连云港,22000 |
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| 摘 要： | 目的探讨肺部细菌感染患者血清降钙素原(PCT)水平的变化及其临床意义。方法应用双抗夹心免疫发光法测定血浆PCT含量;对30例肺部细菌感染组治疗前后以及30例健康志愿者(正常对照组)分别进行血浆PCT水平的测定。结果细菌感染组治疗前PCT值为(34.96±6.83)ng/mL,正常对照组PCT值为(0.41±0.18)ng/mL,差异有显著性(P<0.05);细菌感染组治疗后PCT值为(7.64±1.97)ng/mL,与治疗前相比,差异有统计学意义(P<0.05)。结论血清PCT检测在肺部细菌感染的早期诊断中有一定价值,动态检测PCT水平有助于评估治疗效果,协助临床判断病情转归。
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| 关 键 词： | 降钙素原 肺部细菌感染 动态监测 |
The Changes and Clinical Implications of Serum Procalcitonin in Pulmonary Bacterial Infection |
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| WU Xing-ping. The Changes and Clinical Implications of Serum Procalcitonin in Pulmonary Bacterial Infection[J]. Guide of China Medicine, 2011, 9(23): 36-37 |
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| Authors: | WU Xing-ping |
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| Affiliation: | WU Xing-ping(Department of Respiratory Medicine,the First People′s Hospital of Lianyungang,Lianyungang 222000,China) |
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| Abstract: | Objective To investigate the changes and clinical implications of serum procalcitonin（PCT） in pulmonary infection.Methods PCT was determined by immunoluminometric assay（ILMA）.Serum PCT level and their dynamic change of 30 patients with bacterial infection and 30 healthy volunteers as the control group.Results The serum level of PCT in the bacterial infection group was（34.96±6.83）ng/mL,which were much higher than those in the control group（0.41±0.18）ng/mL.There was statistic difference between the control group and infection group（P0.05）.When they have been cured,the level of PCT for patients decreased to（7.64±1.97）ng/mL,which were significantly lower than in exacerbation（34.96±6.83）ng/mL,and there was statistic difference between them（P0.05）.Conclusion The determination of serum PCT assists the early diagnosis,estimation and prognosis of pulmonary bacterial infection.Monitoring dynamically PCT level will help to evaluate the curative effect. |
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| Keywords: | Procalcitonin Pulmonary bacterial infection Monitoring dynamically |
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