Mechanisms of hemostimulating effect of granulocytic colony-stimulating factor during cytostatic treatment |
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| Authors: | E. D. Gol'dberg A. M. Dygai V. V. Zhdanov G. N. Krivopalova V. I. Masycheva N. M. Pustoshilova N. S. Pushkareva E. V. Simanina S. A. Sinichkina |
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| Affiliation: | (1) Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Science, Berdsk;(2) Engineering-and-Technological Institute of Bioactive Compounds, “Vector” Research-and-Production Association, Berdsk |
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| Abstract: | Original Russian-made preparation of human recombinant granulocytic colony-stimulating factor possessesin vitro activity similar to that of standard preparation, activatesin vivo production of humoral factors by adherent cells of the hemopoiesis-inducing microenvironment, and stimulates hemopoiesis in the bone marrow at various levels. Translated fromByullenten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 8, pp. 194–199, August, 1999 |
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| Keywords: | granulocytic colony-stimulating factor granulocytopoiesis microenvironment |
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