| 复方川芎颗粒的质量标准研究 |
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| 引用本文： | 姚荧,徐以亮,陈燕飞,黄银涛.复方川芎颗粒的质量标准研究[J].中国药房,2012(47):4491-4492. |
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| 作者姓名： | 姚荧 徐以亮 陈燕飞 黄银涛 |
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| 作者单位： | [1]无锡市妇幼保健院,江苏无锡214002 [2]江阴天江药业有限公司,江苏无锡214434 |
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| 基金项目： | （本研究受无锡市科技发展指导性（社会发展）项目（锡科农[2010]150号）资助.） |
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| 摘 要： | 目的:建立复方川芎颗粒的质量标准。方法:采用薄层色谱(TLC)法对复方川芎颗粒中的川芎、当归进行定性鉴别;用高效液相色谱法测定其中阿魏酸含量。结果:TLC分离好,斑点清晰,阴性对照无干扰;阿魏酸进样量在0.027～0.270μg范围内与峰面积积分值呈良好的线性关系(r=0.9999),平均加样回收率为97.92%,RSD=0.79%(n=6)。结论:所建标准可用于复方川芎颗粒的质量控制。
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| 关 键 词： | 复方川芎颗粒 薄层色谱法 高效液相色谱法 阿魏酸 质量标准 |
Study on the Quality Standard of Compound Chuanxiong Granules |
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| YAO Ying,CHEN Yan-feiWuxi Maternal and Child Health Hospital of Jiangshu Province,Jiangsu Wuxi,China XU Yi-liang,HUANG Yin-tao.Study on the Quality Standard of Compound Chuanxiong Granules[J].China Pharmacy,2012(47):4491-4492. |
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| Authors: | YAO Ying CHEN Yan-feiWuxi Maternal and Child Health Hospital of Jiangshu Province Jiangsu Wuxi China XU Yi-liang HUANG Yin-tao |
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| Institution: | (Jiangyin Tianjiang Pharmaceutical Co., Ltd., Jiangsu Wuxi 214434, China) |
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| Abstract: | OBJECTIVE：To establish the quality standard of Compound chuanxiong granules. METHODS：Ligusticum chuanxiong and Angelicae sinensis were indentified by TLC qualitatively. The content of ferulic acid in Compound chuanxiong granules was determined by HPLC. RESULTS： TLC spots were clear and well-separated without interference from negative sample. The linear ranges was 0.027～0.270 μg for ferulic acid（r=0.999 9） with an average recovery of 97.92%（RSD=0.79%,n=6）. CONCLUSION： Established standard is suitable for quality control of Compound chuanxiong granules. |
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| Keywords: | Compound chuanxiong granules TLC HPLC Ferulic acid Quality standard |
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