麝香保心丸治疗冠心病心绞痛伴高脂血症临床研究

目的:探讨麝香保心丸治疗冠心痛心绞痛伴高脂血症的临床疗效.方法:将109例冠心痛心绞痛伴高脂血症患者随机分两组.对照组50例常规服用硝酸异山梨酯片(消心痛)、酒石酸美托洛尔片(倍他乐克)及阿斯匹林肠溶片;治疗组59例在对照组基础上加服麝香保心丸治疗.每次2粒,每日3次.4周后观察心绞痛、心电图、血脂的变化情况.结果:心绞痛疗效:治疗组有效率为94.9％,对照组有效率为82.0％,两组比较有显著性差异(P＜0.05);减少心绞痛发作频率和缩短发作持续时间治疗组优于对照组(P＜0.05);心电图疗效:治疗组有效率为88.1％,对照组有效率为76.0％,两组比较有显著性差异(P＜0.05).治疗后治疗组胆固醇、三酰甘油、低密度脂蛋白、高密度脂蛋白与对照组比较有显著性差异(P＜0.05).结论:麝香保心丸治疗冠心痛心绞痛伴高脂血症临床疗效显著,临床耐受性好,安全性高,适合冠心痛心绞痛伴高脂血症患者长期服用.

Clinical Research of Shexiang Baoxin Pill in Treating Angina Pectoris with Hyperlipoidemia

Objective ：To discuss the clinical curative effects of Shexiang Baoxin Pill in treating angina pectoris with hyperlipoidemia. Methods： 109 cases of patients of angina peetoris with hyperlipoidemia were randomly divided into two groups. The control group （50 cases） was treated by routine western medicine of Isosorbide Dinitrate tablet, Betaloe tablet and Aspirin;the observation group （59 cases） was given Shexiang Baoxin Pill based on the control group, two pellets once, three times per day. Variation situation of angina peetoris, electrocardiogram and blood fat were observed after treatment of four weeks. Results ： The effective rate of the observation group was 94. 9% ,the control group was 82/0% , there was significant difference between two groups （P 〈 0.05 ） ;the observation group was superior to the control group in reducing the occurring frequency of angina peetoris and shortening occurring duration（ P 〈 0.05 ） ;curative effect of electrocardiogram：effective rate of the observation was 88.1%, the control group was 76.0%, there was significant difference between two groups （ P 〈 0.05 ）. Conclusion ： Shexiang Baoxin Pill has remarkable curative effect in treating angina pectoris with hyperlipoi- demia, has good clinical tolerance and high safety,is suitable for patients of angina peetoris with hyperlipoidemia long-term taking.