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盐酸西替利嗪治疗常年性变应性鼻炎的临床观察
引用本文:陆秋天,梁建平,陈慧,袁弘. 盐酸西替利嗪治疗常年性变应性鼻炎的临床观察[J]. 药学与临床研究, 2002, 10(2): 33-34
作者姓名:陆秋天  梁建平  陈慧  袁弘
作者单位:广西壮族自治区人民医院,南宁,530021
摘    要:目的:观察西替利嗪治疗常年性变应性鼻炎(PAR)的疗效及不良反应。方法:给予136例PAR患者每日口服西替利嗪10mg,连续4周,禁用其他抗过敏药或滴鼻剂。结果;随访1年,显效87例(63.97%),有效40例(29.41%),无效9例(6.62%),总有效率93.38%,无严重并发症发生。结论:西替利嗪治疗PAR具有疗效显著,不良反应少等优点,有较好临床应用价值。

关 键 词:常年性变应性鼻炎  西替利嗪  疗效
修稿时间:2002-01-30

Observation of Clinical Efficacy of Cetirizine Hydrochloride in 136 Cases with Perennial Allergic Rhinitis
Lu Qiutian,Liang Jianping,Chen Hui,Yuan HongThe People''''s Hospital of Guangxi Zkuang Autonomous Region. Observation of Clinical Efficacy of Cetirizine Hydrochloride in 136 Cases with Perennial Allergic Rhinitis[J]. Pharmacertical and Clinical Research, 2002, 10(2): 33-34
Authors:Lu Qiutian  Liang Jianping  Chen Hui  Yuan HongThe People''''s Hospital of Guangxi Zkuang Autonomous Region
Affiliation:Naming 530021
Abstract:AIM: The purpose is to study the effect of cetirizine hydrochloride on perennial allergic rhinitis (PAR). METHODS: 136 cases of PAR were treated by cetirizine hydrochloride. Each patient took cetirizine hydrochloride, 10 mg per day for 4-weeks, and other drugs were forbidden. Cetirizine hydrchloride was used for improving the recurrence symptoms in one year follow-up. RESULTS: The overall effective (excellent/good) rate was 93. 38% (excellent 63. 97% , good 29. 41%). Total symptom score (TSS) before treatment and TSS after treatment had significant difference (P<0. 01). The recurrence rate was 68. 38% , but 84 recurrence cases symptoms were lighter than those of pre-treatment. All treatments were well tolerated, and no serious adverse events occurred. CONCLUSION: The curative effect of cetirizine hydrchloride in the treatment for PAR is satisfactory, and the adverse reaction is slight, so it is one of the efficacious antihistamines to treat PAR.
Keywords:Perennial allergic rhinitis  Cetirizine hydrochloride  Clinical efficacy
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