| exosome的研究进展 |
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| 引用本文： | 杜嘉瑞,鞠砚.exosome的研究进展[J].中国神经肿瘤杂志,2006(4). |
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| 作者姓名： | 杜嘉瑞 鞠砚 |
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| 作者单位： | 吉林大学第一附属医院神经外科 吉林大学第一附属医院神经外科 吉林长春 吉林长春 |
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| 摘 要： | exosome是一种可由多种细胞分泌的纳米量级的膜性小囊泡。经研究后发现,其内含有独特的蛋白质与脂质。这也决定了exosome的生物学功用,如去除细胞生长过程中的废弃蛋白、抗原提呈、信号传导或诱导抗肿瘤免疫反应等。本文就exosome的研究进展做一综述,阐述到目前为止对exosome的生理组成及生物功能的研究成果,并探讨其在生物学应用方面的潜在前景。
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| 关 键 词： | exosome 生物来源 分子组成 生物学功能 |
Progress in the Research of Exosome |
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| Jia-rui Du,Yan Ju.Progress in the Research of Exosome[J].Chinese Journal of Neuro-Oncology,2006(4). |
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| Authors: | Jia-rui Du Yan Ju |
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| Institution: | Jia-rui Du,Yan Ju Department of Neurosurgery,The First Hospital of Jilin University,Changchun 130021,P.R.China |
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| Abstract: | Exosomes are nanometer sized membrane vesicles secreted by a multitude of cells. The protein and lipid compositions are unique and this accounts for their biological functions. This review summarizes the composition and formation of exosome and its biological functions, such as eradication of obsolete proteins, antigen presentation, signal transduction and anti-tumor immune response.We present the recent development in the field of exosome research and the potential biological applications . |
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| Keywords: | Exosome Biogenesis Molecular composition Biological function |
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