灰毡毛忍冬藤化学成分研究

目的:分离鉴定灰毡毛忍冬藤的化学成分。方法:采用各种柱色谱进行分离纯化,通过理化性质和波谱数据分析(MS1,H-NMR1,3C-NMR)进行结构鉴定。结果:从灰毡毛忍冬藤中分离出13个化合物,分别鉴定为:β-谷甾醇(1)、胡萝卜苷(2)、绿原酸(3)、木犀草素(4)、槲皮素(5)、香叶木素-7-O-β-D-葡萄糖苷(6)、山柰酚-3-O-β-D-葡萄糖苷(7)3、,4-O-二咖啡酰奎宁酸甲酯(8)、1,3-O-二咖啡酰奎宁酸(9)、东莨菪素(10)、灰毡毛忍冬皂苷乙(11)、灰毡毛忍冬皂苷甲(12)、圣草酚(13)。结论:其中,化合物6、7、13是首次从该植物中分离得到。

Chemical constituents from stems of Lonicera macranthoides

Objective: To study the chemical constituents of Lonicera macranthoides.Methods: Many chromatography means were used in separation and purification,and the structures of all compounds were identified by the means of spectroscopic analysis(MS,1H-NMR,13C-NMR)and physicochemical properties.Results:13 compounds were elucidated as β-sitosterol(1),daucosterol(2),chlorogenic acid(3),luteolin(4),quercetin(5),diosmetin-7-O-β-D-glucoside(6),kaempferol-3-O-β-D-glucoside(7),3,4-O-di-caffeoylquinic acid methylester(8),1,3-O-di-caffeoylquinic acid(9),scopoletin(10),macranthoidin B(11),macranthoidin A(12),eriodictyol(13).Conclusion: The compounds 6,7 and 13 are obtained from this plant for the first time.