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利用生物转化法制备稀有人参皂苷的研究进展
引用本文:崔玉娜,张怡轩,赵余庆.利用生物转化法制备稀有人参皂苷的研究进展[J].医学教育探索,2009,40(5):676-680.
作者姓名:崔玉娜  张怡轩  赵余庆
作者单位:沈阳药科大学,辽宁 沈阳 110016
基金项目:辽宁省自然科学基金资助项目(20062031,20062069);“省级工程中心建设”基金资助项目(2002403004);沈阳市科技攻关资助项目(1032042-3-01)
摘    要:近些年来,稀有人参皂苷的各种生物活性越来越受到人们的重视。但是由于其天然含量低,使其在药物开发方面受到了限制。而利用生物转化法对人参皂苷的糖链进行结构修饰,已成为获得稀有人参皂苷的重要途径。对产稀有人参皂苷的微生物转化和稀有人参皂苷制备相关的研究进行综述,为稀有人参皂苷的获得、开发与利用提供参考。

关 键 词:稀有人参皂苷  生物转化  微生物细胞    制备

Advances in studies on preparation of rare ginsenosides by biotransformation
CUI Yu-n,ZHANG Yi-xuan,ZHAO Yu-qing.Advances in studies on preparation of rare ginsenosides by biotransformation[J].Researches in Medical Education,2009,40(5):676-680.
Authors:CUI Yu-n  ZHANG Yi-xuan  ZHAO Yu-qing
Institution:Shenyang Pharmaceutical University, Shenyang 110016, China
Abstract:Recent years, bioactivities of rare gisenosides have been paid more and more attention to, but the low content or even no existance in nature makes them difficuilt to be utilized in pharmaceutical development. Howerver, biotransformaion that modifies the structure of gisenosides sugar chains has became an important way to abtain rare gisenosides. Studies on production of rare ginsenosides by micro-biotrasformations and preparations of rare ginsensoides were reviewed in this article which provides the references for obtainment, exploitation, and utilization of rare gisenosides.
Keywords:rare ginsenosides  biotransformation  microorganic cells  enzym  preparation
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