A comparison of spatial clustering and cluster detection techniques for childhood leukemia incidence in Ohio, 1996 – 2003 |
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Authors: | David C Wheeler |
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Institution: | (1) Department of Biostatistics, Emory University, Atlanta, GA, USA |
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Abstract: | Background Spatial cluster detection is an important tool in cancer surveillance to identify areas of elevated risk and to generate hypotheses
about cancer etiology. There are many cluster detection methods used in spatial epidemiology to investigate suspicious groupings
of cancer occurrences in regional count data and case-control data, where controls are sampled from the at-risk population.
Numerous studies in the literature have focused on childhood leukemia because of its relatively large incidence among children
compared with other malignant diseases and substantial public concern over elevated leukemia incidence. The main focus of
this paper is an analysis of the spatial distribution of leukemia incidence among children from 0 to 14 years of age in Ohio
from 1996–2003 using individual case data from the Ohio Cancer Incidence Surveillance System (OCISS). |
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