| 苦瓜茎叶醋酸乙酯部位的化学成分研究 |
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| 引用本文： | 杨振容,成睿珍,李玥,赵静,张丽娟,宋新波.苦瓜茎叶醋酸乙酯部位的化学成分研究[J].国外医药(植物药分册),2014(4):346-348. |
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| 作者姓名： | 杨振容 成睿珍 李玥 赵静 张丽娟 宋新波 |
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| 作者单位： | 天津市滨海新区塘沽中医医院;天津中医药大学; |
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| 摘 要： | 目的研究苦瓜茎叶醋酸乙酯部位的化学成分，为进一步开发利用苦瓜茎叶提供依据。方法采用反复硅胶柱色谱、反相ODS柱色谱、SephadexLH-20等柱色谱进行分离纯化，并根据波谱数据鉴定化合物的结构。结果分离得到3种苦瓜三萜，分别鉴定为苦瓜素I（1）、kuguacinN（2）、3，7．二羟基．23帜）-乙氧基-19．醛基．5，24-二烯醇（3）。结论化合物3为新化合物，命名为23．乙基苦瓜素I。
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| 关 键 词： | 苦瓜 苦瓜三萜 苦瓜素I kuguacin N 3 7-二羟基-23俾） 乙氧基-19-醛基-5 24-二烯醇（23-乙基苦瓜素I） |
Chemical constituents in ethyl acetate fraction from fresh vines and leaves of Momordica charantia |
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| Authors: | YANG Zhen-rong CHENG Rui-zhen LI Yue ZHAO Jing ZHANG Li-juan SONG Xin-bo |
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| Institution: | 1. Tanggu Chinese Medicine Hospital of Tianjin Binhai New Area, Tianjin 300451, China 2. Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China) |
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| Abstract: | Objective To investigate the chemical constituents in ethyl acetate fraction from the fresh vines and leaves of Momordica charantia, so as to provide a basis for the further development and utilization. Methods Chemical constituents were isolated and purified by chromatography on silica gel and octadecylsilanized （ODS） silica gel columns, and the structures were identified on the basis of spectroscopic data. Results Three cucurbitane triterpcnoids were isolated and they were identified as momordicine I （1）, kuguacin N （2）, and 3,7-dihydroxycucurbita-23（R）-ethoxy-5,24-dien-19-al （3）. Conclusion Compound 3 is a new compound named 23-ethyl momordicine 1. |
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| Keywords: | Momordica charantia L cucurbitane triterpenoid momordicine I kuguacin N 3 7-dihydroxycucurbita-23（R）-ethoxy-5 24-dien-19-al （23-ethyl momordicine I） |
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