| 重组活化人凝血因子VII在肝脏移植术中应用 |
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| 引用本文： | 李宏,邓迺封. 重组活化人凝血因子VII在肝脏移植术中应用[J]. 国际麻醉学与复苏杂志, 2006, 0(2) |
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| 作者姓名： | 李宏 邓迺封 |
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| 作者单位： | 天津第一中心医院麻醉科 300192(李宏)，天津医科大学第二附属医院麻醉科 300211(邓迺封) |
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| 摘 要： | 重组活化人凝血因子VII(recombinant factorVIIa,rFVIIa),是一种新型止血药,最初用于治疗存在有因子VIII(FVIII)和因子IX(FIX)抗体(抑制物)的先天性血友病和继发性血友病患者的自发性或手术性出血。目前,已证实该药对控制多种临床出血情况是有益的[1]。1分子结构活化人凝血因子
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Application of recombinant activated factor VII in liver transplantation |
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| LI Hong,DENG Nai-feng. Application of recombinant activated factor VII in liver transplantation[J]. international journal of anesthesiology and resuscitation, 2006, 0(2) |
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| Authors: | LI Hong DENG Nai-feng |
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| Affiliation: | LI Hong~1,DENG Nai-feng~2Department of Anesthesiology,1 st Central Hospital of Tianjin,Tianjin 300192,China |
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| Abstract: | Recombinant factor VIIa(rFVIIa) is a new drug to prevent and control the hemorrhagic episode in certain patients.The rFVIIa is one type of recombinant protein,which gene is cloned and expressed in baby hamster kidney cells,and it can efficiently prevent the hemorrhage in liver transplantation without an increased risk of thrombotic complications.It also can be used in heart surgery and other operation to prevent the hemorrhage.This review will discuss its mechanism and application in liver transplantation. |
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| Keywords: | recombinant factor VIIa liver transplantation |
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