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麻醉与术后认知功能障碍相关机制的研究进展
引用本文:左蕾. 麻醉与术后认知功能障碍相关机制的研究进展[J]. 医学综述, 2013, 19(10): 1847-1849
作者姓名:左蕾
作者单位:左蕾 (重庆医科大学附属第一医院麻醉科,重庆,400016);
基金项目:重庆市卫生局科学技术研究项目(项目编号:20102076)
摘    要:术后认知功能障碍(POCD)是术后出现的一种中枢神经系统的并发症。它是在患者自身病理生理改变的基础上由麻醉以及手术诱发的中枢神经系统的病变。发生POCD的患者多为老年人,在临床上并非少见。POCD严重影响患者术后生活质量,有的患者因此而不能自理生活且干扰药物治疗效果,延长患者住院周期。近年来,麻醉与POCD的关系备受关注,可能为临床上防治POCD提供新的思路。

关 键 词:麻醉  术后认知功能障碍  危险因素

The Research Progress of the Relationship between Anesthesia and Postoperative Cognitive Dysfunction
ZUO Lei,LI Qi-ying,LIU Dan-yan. The Research Progress of the Relationship between Anesthesia and Postoperative Cognitive Dysfunction[J]. Medical Recapitulate, 2013, 19(10): 1847-1849
Authors:ZUO Lei  LI Qi-ying  LIU Dan-yan
Affiliation:. ( Department of Anesthesiology,the First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)
Abstract:On the basis of changes in the pathophysiology of the patient,postoperative cognitive dysfunction(POCD) is a central nervous system lesion induced by anesthesia and surgery.It is considered as a postoperative complication.It is not rare to see that POCD occurs in the elderly.POCD is likely to impair quality of life,constitute a large burden on society,interfere in the therapeutic efficacy and increase the time of hospital stay.Recently,the relationship between anesthesia and POCD has drawn much attention,which may provide a novel approach for prevention and treatment of POCD.
Keywords:Anesthesia  Postoperative cognitive dysfunction  Risk factors
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