| 炎症性肠病发病机制的研究新进展 |
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| 引用本文： | 余世界,董卫国.炎症性肠病发病机制的研究新进展[J].胃肠病学和肝病学杂志,2014(2):124-126. |
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| 作者姓名： | 余世界 董卫国 |
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| 作者单位： | 武汉大学人民医院消化内科,湖北武汉430060 |
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| 摘 要： | 炎症性肠病(inflammatory bowel disease,IBD)是一组反复发作的慢性炎症性肠道疾病,主要包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn’s disease,CD)。其确切的发病机制目前尚不明确,本文主要对遗传因素、免疫因素、环境因素、内质网应激和肠道微生物这五个方面在IBD中的新观点作一概述。
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| 关 键 词： | 炎症性肠病 易感基因 内质网应激 肠道菌群 |
New progress of inflammatory bowel disease |
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| YU Shijie,DONG Weiguo.New progress of inflammatory bowel disease[J].Chinese Journal of Gastroenterology and Hepatology,2014(2):124-126. |
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| Authors: | YU Shijie DONG Weiguo |
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| Institution: | Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China) |
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| Abstract: | Inflammatory bowel disease （IBD） is a group of recurrent chronic inflammatory bowel disease, which includes UC and CD. The exact pathogenesis is unclear. This paper reviews new progress in IBD about genetic factors, immune factors, environmental factors, endoplasmic reticulum stress and intestinal flora. |
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| Keywords: | Inflammatory bowel disease Susceptibility genes Endoplasmic reticulum stress Intestinal flora |
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