温度对去甲肾上腺素引起的大鼠主动脉收缩张力的影响

研究温度对去甲肾上腺素（ＮＥ）引起的动脉血管收缩张力变化的影响及原因。测量３９．５、３６．５、３３．０℃时，在ＮＥ作用下的张力－时间曲线，拟合出两者的函数关系式。并对关系常数进行Ｆ检验。实验结果表明：在三种不同温度下，函数式中的常数Ｘ１间比较有显著性差异，Ｐ〈０．０１；常数Ｘ２间比较无显著性差异，Ｐ〉０．０５。认为ＮＥ引起的血管收缩张力的大小，显然也处于温度的影响之下；随着温度的升高，血管收缩张力

Effects of Temperature on the Vasoconstrictive Force of Norepinephrine in Rat Aorta

This study aimed at the influence of temperature on the vasoconstrictive effect of norepinephrine on rings of rat aorta and at the cause of the change observed. At the temperatures of 39.5 degrees C, 36.5 degrees C and 33.0 degrees C respectively, the vasoconstrictive force-time curve induced by norepinephrine and the equation of function were fitted. Statistical evaluation of the data was performed by F test. The difference was statistically significant (P < 0.01) among the three groups for relation constant X1 of function equation, but no significant difference (P > 0.05) was noted among the three groups for relation constant X2. Our experiments demonstrated that norepinephrine-induced vasoconstrictive force, in rat aorta, was obviously modulated by temperature. As the temperature of rat aorta was raised, the vasoconstrictive force and vasoconstrictive speed increased, and the effects of norepinephrine on vasculature were raised. The results suggest that the constant X1 for vasoconstrictive force is a factor sensitive to temperature.