| THE DETECTION OF CD56 AND EPSTEIN-BARR VIRUS IN T-CELL LYMPHOMAS |
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| 作者姓名： | 江庆萍 林汉良 周慕珩 |
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| 作者单位： | Jiang Qingping * Lin Hanliang ** Zhou Muheng ** *Department of Pathology，Zhujiang Hospital，The First Military Medical University，Guangzhou 510282 ** Department of Pathology，Sun Yat Sen University of Medical Sci |
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| 摘 要： | Ｒｅｃｅｎｔｌｙ，ｔｈｅｉｍｐｏｒｔａｎｃｅｏｆＥＢＶｉｎＴＣＬｐａｔｈｏｇｅｎｅｓｉｓｗａｓｎｏｔｉｃｅｄｍｏｒｅａｎｄｍｏｒｅ．１Ｆｕｒｔｈｅｒ，ｉｔｈａｓｂｅｎｄｉｓｃｏｖｅｒｅｄｔｈａｔＴＣＬｓｗｉｔｈＥＢＶｉｎｆｅｃｔｉｏｎｏｆｔｅｎｅｘｐ...
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The detection of CD56 and epstein-barr virus in T-cell lymphomas |
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| Qingping Jiang,Hanliang Lin,Muheng Zhou.THE DETECTION OF CD56 AND EPSTEIN-BARR VIRUS IN T-CELL LYMPHOMAS[J].Chinese Journal of Cancer Research,1998,10(3):208-210. |
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| Authors: | Qingping Jiang Hanliang Lin Muheng Zhou |
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| Institution: | (1) Department of Pathology, Zhujiang Hospital, The First Military Medical University, 510282 Guangzhou;(2) Department of Pathology, Sun Yat-Sen University of Medical Sciences, China |
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| Abstract: | Objective: To study the relationship between EBV infection and the expression of CD56 in T cell lymphomas (TCLs). Methods: 46 cases of TCLs and 15 cases of reactive hyperplasia of lymphonodes (RHs) were detected CD56 by immunohistochemistry and EBERs by in situ hybridization. Results: 8 cases of 46 TCLs (17.4%) showed CD56 positive. On sites, CD56 positive rate of nasopharyngeal TCLs was highest (5/17, 29.4%), and on subtypes, that of DLs was highest (6/16, 37.5%). Additionally, 4 RHs were also CD56 positive. Of 46 TCLs, 24 showed expression of EBERs. There were only 4 TCLs expressing both CD56 and EBERs. Conclusion: The expression of CD56 was not especially for TCLs that EBV infected. EBV infection was not related with CD56 positive TCLs. The findings also suggested the expression of CD56 in TCLs be possibly related to original sites and subtypes of TCLs. |
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| Keywords: | T cell lymphoma Epstein Barr virus CD56 |
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