夜间BiPAP治疗稳定期高碳酸血症患者的疗效观察

目的 :观察双水平正压通气 (BiPAP)治疗稳定期高碳酸血症患者的疗效。方法 :应用BiPAP呼吸机对18例稳定期高碳酸血症患者采用双水平正压通气 ,观察治疗前后动脉血气及稳定期脉氧饱和度 (SpO2)和经皮二氧化碳 (TcCO2)的变化。结果 :通过治疗18例患者的PaO2 及REM期SpO2 有明显的提高 (P<0.001) ,PaCO2 及REM期的TcCO2 显著下降(P<0.001)。且治疗后与治疗1月后相比效果基本稳定。结论 :稳定期高碳酸血症的患者夜间予双水平正压通气治疗 ,可以提高患者的生活质量 ,改善白天血气、睡眠质量和运动耐受力 ,减少气管插管的机率。

Nocturnal non-invasive mechanical ventilation support in the management of stable hypercapnic respiratory failure

Objective:To evaluate the effects of nasal or face mask mechanical ventilation on treatment of stable hypercapnic respiratory failure.Methods:The study included 18 patients with stable hypercapnic respiratory failure received nocturnal non-invasive mechanical ventilation support,and artery blood gases and SpO2 in REM stage were analyzed before and after treatment.Results:After treatment PaO2 and SpO2 in REM stage were improved markedly(P<0.001),PaCO2 and TcCO2 in REM stage were decreased(P< 0.001). It was more effective in treating hypercapnic than hypocemia when we used BiPAP.Conclusion:Nocturnal non-invansive mechanical ventilation can improve daytime artery blood gases,the quality of life and reduce the opportunity of EMT.