| 抗滋养细胞膜抗原( T A) Ig G 类抗体诊断原因不明性流产的临床价值 |
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| 引用本文： | 张艳辉,韩丽英,李荷莲.抗滋养细胞膜抗原( T A) Ig G 类抗体诊断原因不明性流产的临床价值[J].吉林大学学报(医学版),1999,25(4):418-420. |
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| 作者姓名： | 张艳辉 韩丽英 李荷莲 |
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| 作者单位： | 第二临床学院妇产科 ，长春 130041 |
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| 摘 要： | 目的：探讨抗滋养细胞膜抗原（ Ｔ Ａ） Ｉｇ Ｇ 类抗体与原因不明性流产的关系。方法：采用酶联免疫吸附实验（ Ｅ Ｌ Ｉ Ｓ Ａ）检测９５例流产妇女及５２例正常妊娠妇女血清中抗滋养细胞膜抗原（ Ｔｒｏ ｐｈｏｂｌａｓｔ ａｎｔｉｇｅｎ， Ｔ Ａ） Ｉｇ Ｇ 类抗体的水平。结果：流产妇女血清中抗滋养细胞膜抗原 Ｉｇ Ｇ 类抗体水平明显高于正常妊娠妇女（ Ｐ＜ ０００１）；流产妇女血清抗滋养细胞膜抗原 Ｉｇ Ｇ 类抗体水平与孕次呈正相关（ｒ＝ ０．９１， Ｐ＜ ００５）。结论：血清中抗滋养细胞膜抗原 Ｉｇ Ｇ 类抗体水平可以作为流产免疫因素的一个特异性的辅助诊断指标。
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| 关 键 词： | 滋养细胞膜抗原 抗体 流产 ELISA |
| 修稿时间： | 1998年9月1日 |
Clinical value of diagnosing cause-unknown abortion by detecting anti-trophoblast antigen (TA)antibody (IgG) level |
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| Zhang Yanhui,Han Liying,Li Helian.Clinical value of diagnosing cause-unknown abortion by detecting anti-trophoblast antigen (TA)antibody (IgG) level[J].Journal of Jilin University: Med Ed,1999,25(4):418-420. |
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| Authors: | Zhang Yanhui Han Liying Li Helian |
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| Abstract: | Objective:To study the correlation between the anti trophoblast antigen (TA) antibody (IgG) and cause unknown aborition.Methods:The anti trophoblast antigen antibody from 95 abortion women and 52 normol pregnant women was measured by enzyme linked immunosorbent assay (ELISA).Results:①The level of anti trophoblast antigen antibody in abortion women was significantly higher than that in normal pregnant women ( P <0 001).②There was a significant correlation between the level of anti trophoblast antigen antibody in sera of abortion woment and the frequency of pregnancy ( r =0.91, P <0 05).Conclusion:Detecting anti trophoblast antigen antibody in sera can be used as a distinctive and supplementary references of immunological abortion. |
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| Keywords: | anti trophoblast antigen antibody abortion ELISA |
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