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Disturbances of saccadic eye movements in monkeys during development of MPTP-induced syndrome |
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| Authors: | Tereshchenko L V Yudin A G Kuznetsov YuB Latanov A V Shul'govskii V V |
| Institution: | (1) Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov Moscow State University, Russia |
| Abstract: | Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP- syndrome. Different disturbances of large- and small-scale saccades were found. |
| Keywords: | idiopathic parkinsonism 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine saccade monkey |
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