| 三嗪类新化合物的合成研究 |
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| 引用本文： | 三嗪类新化合物的合成研究[J]. 中国药科大学学报, 2002, (4): 6-8. |
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| 作者姓名： | 钟毅 毕小玲 尤启冬 周伟澄 |
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| 作者单位： | 1. 中国药科大学药物化学教研室,南京,210009
2. 上海医药工业研究院,上海,200437 |
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| 摘 要： | 以盐酸羟胺为原料，经N－酰化、水解、加成、环合等反应合成三嗪类新化合物（Ia-c)，未见文献报道，结构经红外光谱、核磁共振光谱、高分辨质谱确证。
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| 关 键 词： | 三嗪类新化合物 合成工艺 盐酸羟胺 N－酰化 水解 加成 环合 |
| 文章编号： | 1000-5048(2002)04-0268-03 |
Synthesis of New Triazine Derivatives |
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| Synthesis of New Triazine Derivatives[J]. Journal of China Pharmaceutical University, 2002, (4): 6-8. |
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| Authors: | ZHONG Yi BI Xiao Ling YOU Qi Dong ZHOU Wei Cheng |
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| Affiliation: | ZHONG Yi,BI Xiao Ling,YOU Qi Dong,ZHOU Wei Cheng 1 Department of Pharmaceutical Chemistry,China Pharmaceutical University,Nanjing 210009, 1Shanghai Institute of Pharmaceutical Industry,Shanghai 200437,China |
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| Abstract: | New triazine derivatives(1-{a~e}), which had not been reported previously, were synthesized from oxammonium hydrochloride, through N acylation, O alkylation, hydrolysis, addition and cyclization.Their structures were confirmed by IR? 1HNMR a |
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| Keywords: | Antitrypanosomal New triazine derivatives Synthesis |
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