| 盐酸胺碘酮片的溶出度研究 |
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| 引用本文： | 童荣生. 盐酸胺碘酮片的溶出度研究[J]. 医药导报, 2001, 20(4): 244-245 |
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| 作者姓名： | 童荣生 |
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| 作者单位： | 四川省人民医院, |
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| 摘 要： | 目的建立盐酸胺碘酮片的溶出度测定方法。方法以1%十二烷基硫酸钠为溶出递质,转速100r*min-1;对进口及国产5个厂家的样品进行了溶出度测定。结果不同厂家样品的溶出度差异极显著(P＜0.01)。结论有必要对该产品进行溶出度检查,以保证临床用药安全有效。
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| 关 键 词： | 盐酸胺碘酮片 溶出度 质量控制 抗心律失常药 |
| 文章编号： | 1004-0781(2001)04-0244-02 |
| 修稿时间： | 2000-08-04 |
Study on Dissolution of Amidarone Hydrochloride Tablets |
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| TONG Rong-sheng. Study on Dissolution of Amidarone Hydrochloride Tablets[J]. Herald of Medicine, 2001, 20(4): 244-245 |
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| Authors: | TONG Rong-sheng |
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| Abstract: | Objective: To establish a method for the determination of dissolution of amiodarone hydrochloride tablets. Methods: Samples from five different factories were tested by the paddle method with the dissolving medium of 1% SLS. Results: The results showed that there were very significant differences(P<0.01) in dissolution parameters among the tested samples. Conclusion: It is necessary for testing the dissolution of the amiodarone product to control its quality and ensure clinical efficacy and safety. |
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| Keywords: | Amiodarone hydrochloride tablet Disolution |
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