石家庄地区部分健康成人血清尿酸参考值调查分析

目的确定石家庄地区健康成人不同性别、不同年龄组的血清尿酸参考值范围。方法将1721例自20～60岁每间隔10岁男、女各分为一组,60岁以上者分为男、女两组,每组至少120例 将〈50岁的各年龄组视为青壮年,〉50岁年龄组视为中老年。均采用罗氏全自动生化分析仪检测血清尿酸浓度。结果本调查研究中男、女血清尿酸浓度均呈正态分布,经统计学分析表明,同年龄组男性和女性血清尿酸浓度比较差异有统计学意义（P〈0.001） 男性、女性青壮年组与中老年组血清尿酸浓度比较差异亦有统计学意义（P〈0.001）。男性除20～29年龄组外,各年龄组均数与男性总体均数之间比较差异无统计学意义（t=2.082,P=0.039 t=0.570,P=0.5790 t=0.156,P=0.876 t=-1.976,P=0.050 t=0.793,P=0.429） 女性除20～29年龄组外,各年龄组均数与总体均数比较差异均有统计学意义（t=-2.065,P=0.002 t=-3.188,P=0.002 t=2.859,P=0.005 t=4.514,P〈0.001）。结论血清尿酸浓度水平与年龄、性别有关,石家庄地区健康成人血清尿酸值有逐渐上升趋势,与现用正常参考值区间有一定差别,各实验室有必要建立自己的血清尿酸正常参考值区间并以此作为诊断的标准。

Investigation Analysis and Reference Value of Serum Uric Acid in Healthy Adults in the City of Shijiazhuang

Objective To determine the reference intervals of serum uric acid in the healthy adults of both sexes and different ages in Shijiazhuang.Methods The serum uric acid levels from 1721 healthy adults of Shijiazhuang were determined by Roche Total auto chemistry analyzer.Results Serum uric acid level distribution was logarithm normal distribution.The levels were significantly different between ages and sexes.In the same age group,serum uric acid values in males were higher than those in females(P<0.001).There w...