晚发性维生素K缺乏致颅内出血62例临床分析

目的:对晚发性维生素K缺乏致颅内出血患儿的临床诊治进行分析,并探讨防治措施。方法:对2002年1月～2006年12月期间我科收治的62例晚发性维生素K缺乏致颅内出血患儿的临床资料进行汇总、分析。结果:62例患儿中,治愈36例,好转16例,放弃6例,死亡4例。对存活者中26例进行随访6个月～5年,17例存在不同程度后遗症。结论:晚发性维生素K缺乏致颅内出血是小儿死亡和致残的主要因素,早期诊断,早期治疗,减少误诊,加强预防,对提高治愈率,降低发病率,减少后遗症,有重要的临床意义。

Clinical analysis on 62 cases with delayed vitamin K deficiency induced intracranial hemorrhage

Objective:To analyze the clinical diagnosis and treatment of delayed vitamin K deficiency induced intracranial hemorrhage,and explore preventive measures.Methods:Clinical data of 62 cases with delayed vitamin K deficiency induced intracranial hemorrhage from January 2002 to December 2006 were analysed and summarized.Results:Among 62 infants,36 infants were cured,16 infants got better,6 infants gave up treatment and 4 infants were dead.26 alive infants were followed up for 6 months～5 years,and 17 infants were found with sequelae to different degree.Conclusion:Delayed vitamin K deficiency induced intracranial hemorrhage is a major factor of death and deformity in infants.Early diagnoses,early treatment,less misdiagnosis,reinforcing prevention may reduce prevalence rate and sequelae.