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Endocarditis due to glycopeptide-intermediate Staphylococcus aureus: case report and strain characterization
Authors:Andrade-Baiocchi Soraya  Tognim Maria Cristina B  Baiocchi Otavio C G  Sader Helio S
Affiliation:Laboratório Especial de Microbiologia Clínica (LEMC), Division of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
Abstract:We report a case of infective endocarditis due to vancomycin-intermediate Staphylococcus aureus (VISA) that did not respond to high doses of vancomycin. Initial vancomycin MIC of the last isolate recovered from blood was 8 micro g/mL, but could be induced up to 32 micro g/mL by consecutive growing with vancomycin. Clinical response was only accomplished when linezolid was included in therapy.
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