急性脑卒中患者C反应蛋白测定的临床意义

目的 :探讨C -反应蛋白 (CRP)浓度和白细胞数在急性脑卒中患者血中的浓度变化及其临床意义。方法 :将 1 1 1例急性脑卒中患者分为脑出血组 (2 9例 )和脑梗死组 (82例 ) ,入院 48h内进行CRP浓度和白细胞数测定。CRP浓度测定采用透射比浊法。结果 :急性脑出血组与脑梗死组比较 ,CRP浓度及白细胞数升高 ,差异有显著性 (P <0 0 5 ,P <0 0 1 ) ;二组病死率比较 ,差异也有显著性 (P <0 0 1 )。结论 :血CRP浓度和白细胞数升高对急性脑卒中病的发病机制研究、初步诊断及预后的判断有显著的临床意义

The clinical significance of serum C-reactive protein (CRP) assay for acute cerebral stroke

Objective:To observe the clinical significance of serum CRP and leukocyte count level in patients with acute cerebral stroke.Methods:111 cases of acute cerebral stroke were divided into two groups,one was cerebral hemorrhage,another was cerebral infarction.Serum CRP and leukocyte count level were measured within 48h after onset of acute cerebal stroke.Serum CRP level was examined by nephelometry.Results:Compared cerebral infarction group with cerebral hemorrhage group,both the CRP and leukocyte count level for acute cerebral hemorrhage group were higher(P<0 05,P<0 01),fatality rate was also significantly higher in the cerebral hemorrhage group(P<0 01).Conclusions:Increasing CRP and leukocyte count level may have clinical significance for the acute cerebral stroke in pathogenesis:initial diagnosis and prognosis.