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颅脑损伤患者血清C-反应蛋白和血糖水平的动态变化及其意义
引用本文:蔡朝民,曹建华,陈群蓉,李宏伟. 颅脑损伤患者血清C-反应蛋白和血糖水平的动态变化及其意义[J]. 检验医学与临床, 2009, 6(9): 650-651
作者姓名:蔡朝民  曹建华  陈群蓉  李宏伟
作者单位:广东省深圳市宝安区人民医院/南方医科大学附属宝安医院,518101;广东省深圳市宝安区人民医院/南方医科大学附属宝安医院,518101;广东省深圳市宝安区人民医院/南方医科大学附属宝安医院,518101;广东省深圳市宝安区人民医院/南方医科大学附属宝安医院,518101
摘    要:目的研究颅脑损伤患者血清C-反应蛋白(CRP)、血糖(Glu)水平的动态变化及其意义。方法97例颅脑损伤患者按照病情计分法分为重型组(29例)、中型组(31例)、轻型组(37例)3组,35例健康体检者为健康对照组。用生化分析仪测定颅脑损伤患者伤后6h、1d、3d、14d血清中CRP、Glu水平。结果颅脑外伤患者伤后6h血清CRP、Glu含量均有不同程度升高,与健康对照组比较差异均有统计学意义(P〈0.01)。颅脑损伤患者CRP和Glu水平与患者入院时的GCS评分呈负相关,与其病情呈正相关,重型组患者血清cRP、Glu升高最为明显;中型和轻型组次之,3组之闻的差异有显著性;病情重和预后差的患者其CRP、Glu水平升高幅度大且持续时间更长。结论血清CRP、Glu水平监测可作为颅脑损伤严重程度评价的指标,动态观察颅脑外伤患者血清CRP、Glu水平对疗效观察和预后判断具有重要价值。

关 键 词:颅脑外伤  C-反应蛋白  血糖  预后

Clinical significance of dynamic changes of C-reaction protein and glucose in patients with traumatic brain injury
CAI Chao-min,CAO Jian-hua,CHEN Qun-rong,Li Hong-wei. Clinical significance of dynamic changes of C-reaction protein and glucose in patients with traumatic brain injury[J]. Laboratory Medicine and Clinic, 2009, 6(9): 650-651
Authors:CAI Chao-min  CAO Jian-hua  CHEN Qun-rong  Li Hong-wei
Affiliation:Affiliated Shenzhen Baoan Hospital of South Medical University
Abstract:Objective To study the clinical values of the dynamic changes of serum C-reaction protein(CRP)and glucose(Glu)in the patients with traumatic brain injury.Methods 97 cases of traumatic brain injury were divided into three groups(gentle,miled,moderate and severe)based on the GCS scores,and 35 cases of healthy people were used as controls.The concentrations of CRP and Glu in serum were determined by biochemical analyzer at 6 h,on 1 d,3 d,14 d after injury.Results The levels of serum CRP and Glu were significan...
Keywords:traumatic brain injury  C-reactive protein  glucose  prognosis  
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