无痛胃镜检查1000例临床研究

目的探讨无痛胃镜检查术的优越性和安全性。方法应用丙泊酚行无痛胃镜检查1000例,常规胃镜检查1000例作为对照。记录所有患者不适反应以及心率(HR)、血氧饱和度(SpO2)、血压(BP)的变化。结果无痛组患者咳嗽、咽痛等不适反应的发生率明显低于常规胃镜检查组,二者有显著性差异(P<0.01);96%的无痛组患者愿意再次接受胃镜检查,较常规组(22.0%)有显著性差异(P<0.01)。两组检查前或麻醉前HR、SBP、DBP、SpO2均正常,无痛组检查中、检查后上述指标同检查前比较无显著性差异(P>0.05),常规组检查中HR、SBP、DBP升高,与检查前差异有显著意义(P<0.05),检查中两组HR、SBP、DBP比较,差异有显著意义(P<0.05)。结论无痛胃镜检查是一种安全、有效的检查方法。

Clinical Study on Painless Gastroscopy in 1000 Patients

Objective To investigate the superiority and safety of painless gastroseopy. Methods 1000 patients in painless gastroscopy group were treated with propofol. Control group comprised 1000 normal gastroscopy subjects. Procedure related parameters, such as cough and angina were prospectively assessed. Vital signs （heart rate, blood pressure and oxygen saturation） were continuously monitored in all patients. Result The incidence rate of cough and angina in painless gastroscopy group were significant lower than those in control group （P〈0.01）. 96% patients in painless gastroscopy group compares with 22% patients in control group can accept the same operation again （P〈0.01）. Heart rate, blood pressure and oxygen saturation were normal before the procedure in all patients. The vital signs had no significant change during the procedure, after it or before it in painless gastroseopy group. Heart rate, diastolic pressure and oxygen saturation increased significant during the procedure than before it in normal gastroscopy group（P〈0.05）. Heart rate, diastolic pressure and systolic pressure were significant different during the procedure between two groups（P〈 0.05）. Conclusion Painless gastroscopy is safe and effective.