近视人群角膜前表面Q值及其与球差的相关性

目的:研究近视人群角膜前表面Q值的分布及Q值与角膜前表面球差(C12)、全眼球差(C12)之间的相关性。方法:选择青少年近视眼100眼。使用TOPOLYSER角膜地形图测量角膜前表面的e值,根据Q=-e2,分别求得角膜20°,25°,30°的Q值。WASCA波前像差分析仪和Humphrey角膜地形图仪分别测量并获得全眼球差(6.0mm分析直径)和角膜前表面球差(6.0mm分析直径)的Zernike系数进行分析。结果:20°,25°,30°的Q值分别为-0.144(中位数),-0.213±0.110,-0.277±0.108。6.0mm分析直径下角膜球差和全眼球差分别为0.25712±0.06914μm和0.06630±0.10823μm。25°的角膜Q值与6.0mm角膜球差呈正相关(r=0.673,P=0.000)。25°的角膜Q值与6.0mm全眼球差正相关(r=0.241,P=0.016)。结论:角膜前表面从中央向周边变平坦趋势越来越明显,Q值绝对值越往周边越大。25°角膜前表面Q值与角膜球差显著相关,而与全眼球差相关性弱。

Q-value of corneal anterior surface and its correlation with spherical aberration in myopia population

AIM:To study the distribution of Q-values on corneal anterior surface and analyze its correlation with corneal spherical aberration (C12) and total spherical aberration (C12) respectively. ·METHODS:One hundred myopia eyes were evaluated with TOPOLYSER,Humphrey and WASCA,and the eccentricities (e-value) of corneal surface (20°,25° and 30°),CTS data and total spherical aberration (diameter=6.0mm) were recorded respectively. The e-values were analyzed using formula (Q=-e2) to obtain Q-value. CTS data were analyzed using Matlab software to obtain the spherical aberration of cornea (diameter=6.0mm). ·RESULTS:The Q-values of corneal anterior surface (20°,25° and 30°) were-0.144(M),-0.213±0.110 and-0.277±0.108,respectively. The corneal and total spherical aberrations (diameter=6.0mm) were 0.25712±0.06914μm and 0.06630±0.10823μm,respectively. Q-value of 25° had high correlation (r=0.673,P=0.000) with corneal spherical aberration,but low correlation (r=0.241,P=0.016) with total spherical aberration. ·CONCLUSION:Firstly,corneal surface is much flatter from center to periphery and the absolute values of Q become much larger. Secondly,the Q-value of 25° has high correlation with corneal spherical aberration but low correlation with total spherical aberration.