| 喹硫平与氟西汀治疗抑郁焦虑共病的对照研究 |
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| 引用本文： | 支胜利,尹析凡,徐哲.喹硫平与氟西汀治疗抑郁焦虑共病的对照研究[J].上海精神医学,2010,22(2):78-80. |
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| 作者姓名： | 支胜利 尹析凡 徐哲 |
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| 作者单位： | 湖州市第三人民医院,313000 |
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| 摘 要： | 目的探讨喹硫平与氟西汀对抑郁焦虑障碍共病的疗效和安全性。方法收集抑郁焦虑障碍共病的患者80例,分为喹硫平组和氟西汀组各40例,疗程8周。使用汉密尔顿抑郁量表（HAMD）和汉密尔顿焦虑量表（HAMA）评定疗效,以治疗中出现的症状量表（TESS）评定不良反应。结果喹硫平组有38例、氟西汀组有37例完成8周的研究。治疗8周2组HAMD和HAMA量表减分率无统计学差异,治疗1周末喹硫平组疗效优于氟西汀组。治疗8周后喹硫平组有效率为89.5%（34/38）,氟西汀组为89.2%（33/37）。喹硫平组无转躁患者,氟西汀组1例转躁。喹硫平组头晕的发生率明显多于氟西汀组。结论喹硫平单药治疗抑郁焦虑障碍共病的疗效与氟西汀相当,喹硫平组头晕者较多。
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| 关 键 词： | 喹硫平 抑郁焦虑共病 氟西汀 |
Comparative study of quetiapine versus fluoxetine in the treatment of comorbid anxiety and depression |
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| Zhi Shengli,Yin Xifan,Xu Zhe.Comparative study of quetiapine versus fluoxetine in the treatment of comorbid anxiety and depression[J].Shanghai Archives of Psychiatry,2010,22(2):78-80. |
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| Authors: | Zhi Shengli Yin Xifan Xu Zhe |
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| Institution: | .(The Third People′s of Huzhou,Zhejiang Province,Huzhou 31300 ) |
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| Abstract: | Objective:To examine efficacy and safety of quetiapine versus fluoxetine in the treatment of comorbid depression and anxiety.Methods:80 patients with comorbid depression and anxiety were assigned equally into quetiapine group and fluoxetine group.The course of treatment was 8 weeks.Hamilton depression scale(HAMD) and Hamilton anxiety scale(HAMA) were applied to evaluate efficacy,and treatment emergent symptoms scale(TESS) was applied to evaluate side-effects of drugs.Results:Efficacy was comparable between ... |
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| Keywords: | Quetipine Comorbid depression and anxiety Fluoxetine |
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