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Flavones with free radical scavenging activity fromGoniothalamus tenuifolius
Authors:Kittisak Likhitwitayawuid  Chaweewan Klongsiriwet  Vichien Jongbunprasert  Boonchoo Sritularak  Samphan Wongseripipatana
Institution:Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. Kittisak.L@chula.ac.th
Abstract:From the leaves of Goniothalamus tenuifolius, a new natural product namely 3'-hydroxy-3,5,7,4'-tetramethoxyflavone (1) was isolated, along with seven other known compounds (2-8). Each of these isolates was evaluated for free radical scavenging activity on the DPPH decoloration test. The data obtained in this study suggested that the ortho 3',4'-diphenolic structure was essential for the activity of these flavonol derivatives.
Keywords:Goniothalamus tenuifolius            flavone  free radical scavenging activity  DPPH
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