肠外营养支持机体抗氧化酶活性的变化及其机制的研究

目的：研究肠外营养支持对抗氧化活性的影响。 方法：将临床病人分为肠外营养支持组和对照组，分别观察超氧化物歧化酶和脂质过氧化物活性的变化。 结果：４０例普外科病人接受了肠外营养支持肠外营养支持后超氧歧化酶（ＳＯＤ）的活性升高２１．４％，脂质氧化物（ＬＰＯ）含量下降２１．５％，而对照组病人的ＳＯＤ活性却下降３．２％，ＬＰＯ活性上升５．８％。 结论：研究证明肠外营养支持可减轻氧自由基（ＯＦＲ）的氧化损伤

Study on the change of antioxidase activity by parenteral nutrition support

Objectives:To investigate the effect of parenteral nutrition on the anti oxidant activity in general patients. Methods:Forty patients with general surgery received parenteral nutrition support.The activities of superoxide damutase and lipoxidase were measured before and after nutritional support. Results:The activity of superoxide damutase(SOD) in nutritional support patients increased in 21.14%.The activity of lipoxidase(LPO) decreased in 21.58%.Nevertheless,the activity of SOD in control patients decreased in 3.2 %,the activity of LPO increased in 5.8%. Conclusions:Our study suggested that PN might diminish the injury of oxygen free radiccal(OFR).