| 病毒性肝炎患者血清中有机膦酸脂酶和磷酸二酯酶I的活性变化 |
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| 引用本文： | 王慧芬,韩刚毅,靳晓红,靳仙宝,范西红,吴纯启,江新民. 病毒性肝炎患者血清中有机膦酸脂酶和磷酸二酯酶I的活性变化[J]. 解放军医学杂志, 1994, 0(2) |
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| 作者姓名： | 王慧芬 韩刚毅 靳晓红 靳仙宝 范西红 吴纯启 江新民 |
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| 作者单位： | 解放军第３０２医院，济南军区军事医学研究所，山东省千佛山医院，济南军区总医院 |
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| 摘 要： | 检测了２２１例病毒性肝炎患者血清中有机膦酸脂酶（ＰＥ）和磷酸二脂酶Ｉ（ＰＤＥＩ）的活性变化，并以４１０例献血员为健康对照。结果：急、慢性肝炎及肝硬变病人血清ＰＥ和ＰＤＥＩ活性均显著高于献血员，而肝硬变异常率最高，其次为慢活肝；ＰＥ和ＰＤＥＩ与血清胆红素、转氨酶、球蛋白等无显著相关。提示其测定对慢性肝病，尤其肝硬变的诊断有较好的临床价值。
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| 关 键 词： | 病毒性肝炎，磷酸二酯酶I，有机膦酸酯酶 |
CHANGES IN SERUM PHOSPHODIESTERASE I AND PHOSPHONATE ESTERASE ACTIVITIES IN PATIENTS WITH VIRAL HEPATITIS |
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| Wang Huifen,Han Gangyi,Jin Xiaohong,et al.. CHANGES IN SERUM PHOSPHODIESTERASE I AND PHOSPHONATE ESTERASE ACTIVITIES IN PATIENTS WITH VIRAL HEPATITIS[J]. Medical Journal of Chinese People's Liberation Army, 1994, 0(2) |
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| Authors: | Wang Huifen Han Gangyi Jin Xiaohong et al. |
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| Affiliation: | Wang Huifen,Han Gangyi,Jin Xiaohong,et al. 302nd Hospital of PLA. Beijing 100039 |
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| Abstract: | The changes in serum phosphodiesterase I and phosphonate esterase activities were de- tected in 22 1 patierits with viral hepatitis with 401 healthy donors as controls. The results showed that PDE I and PE activity rose significantly in patients with acute hepatitis , chronic hepatitis and cirrhosis. The serun PDE I or PE activity was not correlated with serum ALT, bilirubin, in these pa- tients. The results suggested that the levels of serum PDE I and PE may serve as indices reflecting chronic liver disease, especially liver cirrhosis. |
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| Keywords: | Viral hepatitis Phosphodiesterase I Phosphonate esterase |
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