多普勒超声心动图对儿童急性肾炎早期左室舒张功能的研究

目的　采用多普勒超声心动图评价儿童急性肾炎 (AGN)早期左室舒张功能 (LVDF)损害的严重程度及疗效观察。方法　将 76例急性肾炎患儿按病情程度分为轻度、重度两组与 5 4例健康对照组进行对照。应用HP - 10 0 0型超声诊断仪 ,分别于治疗前和治疗后 2周测定二尖瓣舒张早期峰值流速 (EV)、二尖瓣舒张晚期峰值流速 (AV)、EV AV比值、舒张早期充盈分数(EI)、舒张晚期充盈分数 (AI)、EI AI比值、E峰加速时间 (AT)、E峰减速时间 (DT)、DT AT比值、肺静脉收缩期最大前向血流速度(S)、舒张期最大前向血流速度 (D)、D S比值、左房内径 (LA)、主动脉内径 (AO)、LA AO比值等 11项指标。结果　EV AV、EI AI、LA AO、D S是判断LVDF损害的重要指标 ;LVDF损害与病情严重程度有关 ,其中 ,EV、EV AV、EI、EI AI、AT、D S随病情加重而降低 ,AV、AI、DT、DT AT、LA AO随病情加重而增高 ;EI、AI、AT、DT、DT AT是评价其疗效的重要指标 ;治疗后 ,LVDF恢复时间晚于临床症状恢复时间。结论　上述指标可动态检测LVDF ,对指导临床诊治具有重要意义。同时该检测方法操作简便易行、重复性强、无痛苦 ,结果较为精确。

A study of the early left ventricular diastolic function among children with acute nephritis through Doppler echocardiography

Objective To evaluate the severity of the defection and treatment effects of the early left ventricular diastolic function(LVDF)among children with acute nephrits through Doppler echocardiography. Methods 76 patients were divided into light group and severe group according to patients conditions, comparing with health group incuding 54 cases. Compare eleven indicators including EV,AV,EV/AV,EI,AI,EI/AI,AT,DT,DT/AT,S,D,D/S,LA,AO,LA/AO before and 2 weeks after treatment. Results EV/AV,EI/AI,LA/AO,D/S were important indicators for LVDF defection.And LVDF defection was connected with the severity of the patients'conditions.EV,EV/AV,EI,EI/AI,AT,D/S decreased with deterioration of patients'conditions.And AV,AI,DT,DT/AT,LA/AO increased with deterioration of patients'conditions.EI,AI,AT,DT,DT/AT were important indicators for treatment effects. After treatment,LVDF recovery was later than clinical symptoms recovery.Conclusions All the indicators above can supervise LVDF dynamically,which is helpful to guide clinical diagnosis and treatment.In the mean time the procedures are easy and applicable with repetition and accurate results,causing no pain to the patients.