Osteomalacia secondary to renal tubular acidosis in a patient with primary Sj?gren's syndrome. |
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Authors: | J T Monte Neto R Sesso G M Kirsztajn L C Da Silva A B De Carvalho A B Pereira |
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Institution: | Department of Medicine, Escola Paulista de Medicina, Sao Paulo, Brazil. |
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Abstract: | We report a case of a 41-year-old woman whose disease manifested as osteomalacia and whose etiological investigation revealed renal tubular acidosis secondary to primary Sj?gren's syndrome. Proximal tubular dysfunction was also present and was documented by increased urinary excretion of beta-2-microglobulin and retinol-binding protein. The patient showed clinical and laboratory improvement after treatment with oral potassium citrate, calcium supplements and steroids. |
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