| 外源性碱性成纤维细胞生长因子促进腮腺创伤修复的实验研究 |
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| 引用本文： | 李健,李嘉琥,宋宇峰,杨振祥,陈晓钟,任渝江. 外源性碱性成纤维细胞生长因子促进腮腺创伤修复的实验研究[J]. 西南国防医药, 2004, 14(2): 132-133 |
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| 作者姓名： | 李健 李嘉琥 宋宇峰 杨振祥 陈晓钟 任渝江 |
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| 作者单位： | 1. 解放军第44医院五官科,贵州,贵阳,550009
2. 贵阳医学院,贵州,贵阳,550001 |
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| 摘 要： | 目的 :观察外用重组碱性成纤维细胞生长因子 (bFGF)对腮腺创伤修复的促进作用。方法 :采用宏观、体视学、显微镜图象分析方法 ,对外用重组bFGF对大鼠腮腺创伤修复的影响进行动态分阶段分析研究。结果 :外用重组bFGF明显促进了肉芽组织和毛细血管的增生 ,增强了创伤性炎症增生反应 ,同时无促进腺泡细胞增生和涎液分泌的作用。结论 :外用重组bFGF促进腮腺创伤的愈合 ,减少腮瘘并发证的发生 ,对腮腺创伤的治疗有重要的临床意义
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| 关 键 词： | 碱性成纤维细胞生长因子 腮腺 创伤 修复 治 |
| 文章编号： | 1004-0188(2004)02-0132-02 |
| 修稿时间： | 2003-10-24 |
Experimental study on the effects of basic fibrolast growth factors on parotid wound healing in rats |
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| LI Jian ,LI Jia-hu ,SONG Yu-feng ,YANG Zhen-xiang ,CHEN Xiao-zhong ,REN Yu-jiang .. Experimental study on the effects of basic fibrolast growth factors on parotid wound healing in rats[J]. Medical Journal of National Defending forces in Southwest China, 2004, 14(2): 132-133 |
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| Authors: | LI Jian LI Jia-hu SONG Yu-feng YANG Zhen-xiang CHEN Xiao-zhong REN Yu-jiang . |
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| Affiliation: | LI Jian 1,LI Jia-hu 2,SONG Yu-feng 2,YANG Zhen-xiang 1,CHEN Xiao-zhong 1,REN Yu-jiang 1.1.Department of Stomatology,No.44 Hospital of PLA,Guiyang 550006.2.Guiyang Medical College,Guiyang 550001. |
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| Abstract: | Objective:To observe the effects of basic fibrolast growth factor(bFGF)on parotid wound healing in rats.Methods:In the remained parotid glands after partial parotidectomy,macroscopic examination,stereological methods and microscopic examination were all used to detect the effects of bFGF on parotid wound healing.Results:It could be observed that bFGF promoted the proliferation of granulation tissue and capillaries but did not promote the proliferation of acinar cells of sialic secretion.Conclusion:bFGF can improve the parotid wound healing and decrease the incidence of fishula of parotid gland,which has important clinical significance for the treatment of parotid wound. |
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| Keywords: | basic fibrolast growth factor parotid wound healing treatment |
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