| 纤溶酶原激活物抑制物和脑血栓 |
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| 引用本文： | 赵晶,戚基萍,王德生.纤溶酶原激活物抑制物和脑血栓[J].黑龙江医学,2002,26(2):95-96. |
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| 作者姓名： | 赵晶 戚基萍 王德生 |
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| 作者单位： | 1. 哈尔滨市第五医院神经内科,黑龙江,哈尔滨,150040
2. 哈尔滨医科大学第一临床医学院,黑龙江,哈尔滨,150001 |
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| 摘 要： | 脑内的纤溶酶原激活物主要是t -PA ,纤溶酶原激活物抑制物 - 1(PAI - 1)相互制约以维持正常血浆纤溶活性 ,PAI- 1水平及活性的变化对血循环中纤溶活性变化起重要作用 ,是脑血栓发病的重要危险因素。文章概述了PAI- 1的结构、分布、活性及其表达 ,以及PAI- 1水平同脑血栓的关系。
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| 关 键 词： | 纤溶酶原激活物 抑制物 脑血栓 |
| 文章编号： | 1004-5775(2002)02-0095-02 |
| 修稿时间： | 2001年12月24 |
Activator of Plasminogen Inhibitor and Cerebral Embolism |
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| ZHAO Jing,QI Ji-ping,WANG De-sheng.Activator of Plasminogen Inhibitor and Cerebral Embolism[J].Heilongjiang Medical Journal,2002,26(2):95-96. |
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| Authors: | ZHAO Jing QI Ji-ping WANG De-sheng |
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| Abstract: | The activator of plasminogen in brain is mainly t-PA. The t-PA restricts activator inhibitor (PAI-1) each othe to maintain the plasma fibrolysis activity. The changes of level and activity of PAI-1 plays important role in changes of fibrolysis activity in blood circulation and is high risk factor of cerebral embolism. This paper had summarized the structure, distribution, activity, expression of PAI-1 and the relation of its level with cerebral embolism. |
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| Keywords: | Activator of plasminogen Inhibitor Cerebral embolism |
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