脑囊尾蚴病患者脑脊液一氧化氮含量分析

目的　探讨脑囊尾蚴病患者脑脊液 (CSF)一氧化氮 (NO)含量以及细胞学成分变化。　方法　采用 Griess法检测 30例脑囊尾蚴病、2 0例结核性脑膜炎 (TBM)及 2 0名健康人 (对照组 ) CSF的 NO水平 ,同时进行其细胞学成分分析。　结果与结论　Griess法能快速、准确地检测 CSF的 NO含量。脑囊尾蚴病组及 TBM组 CSF的 NO水平均明显高于对照组 (P<0 .0 1)。脑囊尾蚴病组 NO水平明显高于 TBM组 (P<0 .0 5 ) ,并以持续的嗜酸性粒细胞增多为主要特点。

Content of Nitric Oxide in Cerebrospinal Fluid from Patients with Neurocysticercosis

Objective To evaluate the relationship between the concentration of nitric oxide (NO) and cytological change in cerebrospinal fluid ( CSF ) and the onset of neurocysticercosis in patients. . Methods. NO Level in CSF was detected in 30 cases of neurocysticercosis, 20 cases of tuberculous meningitis (TBM) and 20 healthy people as control by using Griess method. The cytological components in CSF were also examined.. Results and Conclusion . Griess method was proved to be a rapid and accurate technique for the detection of NO content in CSF. The NO concentration in cases of neurocysticercosis and TBM was significantly higher than that of control(P<0.^01). The neurocysticercosis cases showed the highest CSF NO level which was considerably higher than that of TBM cases(P<0.^05). Among the cytological changes, the neurocysticercosis cases also showed a higher count of eosinophils than that of TBM cases and control (P<0.^01). The NO level and eosinophils count in CSF increased significantly in patients with neurocysticercosis.