Improvement of quality of reporting in randomised controlled trials to prevent hypotension after spinal anaesthesia for caesarean section |
| |
Authors: | A Herdan R Roth D Grass M Klimek S Will B Schauf R Rossaint M Heesen |
| |
Institution: | (1) Department of Anesthesia, Sozialstiftung Bamberg, Buger Str. 80, 96049 Bamberg, Germany;(2) Department of Anesthesia, Erasmus Medical Center, Dr. Molewaterplein, 1101 Rotterdam, The Netherlands;(3) Department of Obstetrics, Sozialstiftung Bamberg, Buger Str. 80, 96049 Bamberg, Germany;(4) Department of Anesthesia, University Hospital of RWTH Aachen, Pauwelsstr. 50, 52074 Aachen, Germany;(5) Klinik f?r An?sthesie, Klinikum Bamberg, Buger Str.80, 96049 Bamberg, Germany; |
| |
Abstract: | Hypotension is a frequent complication of spinal anaesthesia for caesarean section and can threaten the well-being of the
unborn child. Numerous randomised controlled trials (RCTs) dealt with measures to prevent hypotension. The aim of this study
was to determine the reporting quality of RCTs using the Consolidated Standards of Reporting Trials (CONSORT) statement since
low quality can lend false credibility to a study and overestimate the effect of an intervention. We performed a systematic
literature search in PubMed to identify relevant RCTs in a pre-CONSORT period (1990–1994) and a post-CONSORT period (2004–2008).
A comparative evaluation was done between the two periods, and the trials were assessed for compliance with each of the 22
CONSORT items. A total of 37 RCTs was identified. The CONSORT score increased significantly (p < 0.05) from 66.7% (±12.5%) in the pre-CONSORT period to 87.4% (±6.9%) in the post-CONSORT period. A statistically significant
improvement was found for eight items, including randomization, blinding and intention-to-treat analysis. The CONSORT score
in the post-CONSORT era was fairly good, also in comparison to other medical fields. In the post-CONSORT era, reporting of
important items improved, in particular in the domains that are crucial to avoid bias and to improve internal validity. Use
of CONSORT should be encouraged in order to keep or even improve the reporting quality. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|