大鼠电击死后心肌骨骼肌脑的病理学观察

目的 探讨电击死后心肌骨骼肌脑的损伤病理机制。方法 将电线连接大白鼠左前肢和右后肢，右前肢和左后肢，左耳和右后肢，右耳和左后肢，用２２０Ｖ，５ＭＡ交流电定时电击，制造电击死时心肌（左心室）、骨骼肌（四肢）、脑的损伤的动物模型。

Experimental study on cardiac muscle skeletal muscle brain after electrocution

Objective:To explore the pathogenesis of muscle injury skeletal muscle injury brainl injury after electrocution.Methods:for the purpose of establishing on animal model of cardial injury,skeletal muscle injury,brainal injury after electrocution,the right from limbs and the right hind limbs,the right from limbs and left hind limbs,the right ear and the left hind limbs,the left ear and the right hind limbs of the rabbits were connected to the electric apparatus within the alternative of 5mA,220V.Results:Under light microscope,there are fragmentation of myocardical fibrils,the edema around small vasculars,focal necrosis of myocardium;the skeltal muscle fibers are breaking and rupturing,part of muscle fibers become coagulative necrosis;the neuron's cells of brain become degeneration,Nissl body disappeared,chromation become lysis.Under electron microscope,cardiac muscle derangement of mitochoudrious crista,dissolution and slight edema of indivianal crista,transparent thrombogensis,obscure epithelium cells,loose basement memebrane are found.Part of mitochoudrious in muscle fiber are swollen and loss of deranged and fasciculated crista are observed Necrosis of two band material in the skeletal muscle's fiber and dissolution of myofilament are seen.Derangement,fragmentation,swelling and homogenesis of myofilanent and dilifation of sacroplasm net can be found in the local magnified picture of the above.Swollen neuroglia neucleus obscure plasma structure,partial loss of ribosome and abnormal accumulation are found of cerebral tissues.Basement membrane edema,dilitation and exparsion of Will's interittence are also observed.No foot process is seen.There's large amount of vacuole in neuroglia plasma.Conclusion:This study provide the pathological basis for the forensic investigation of cases died from the electric cution of the light microscope and the electric microscope.