核素显像与灌注磁共振成像在短暂性脑缺血中的对比研究

目的通过比较脑葡萄糖代谢显像、脑血流灌注显像及灌注加权磁共振成像(PWI),了解3种检查方法在诊断短暂性脑缺血发作(TIA)中的价值。方法对33例TIA患者(按发病时间分为A、B、C 3组,按双、单侧血管受累分为D、E组)的脑葡萄糖代谢显像、脑血流灌注显像及PWI结果进行对比分析。结果所有TIA患者经上述3种方法检出的阳性率分别为87.88%、84.85%和51.52%,经比较脑血流灌注显像与PWI、脑葡萄糖代谢显像与PWI结果均有显著差异(P=0.001,0.004)。3种方法检出病变的阳性率与发病时间及血管受累情况有关。结论对于TIA的诊断,脑葡萄糖代谢显像、脑血流灌注显像较PWI敏感。

Comparative analysis of cerebral blood flow perfusion image, brain glucose metabolism image and PWI in patients with TIA

Objective To evaluate the clinical value of cerebral glucose metabolism image,cerebral blood flow perfusion image and MR perfusion weighted image(PWI) in patients with TIA by comparing the three methods.Method The results of 33 patients with TIA who underwent all the three examinations were compared.Results The positive rate of brain glucose metabolism image,cerebral blood flow perfusion image and PWI in 33 patients were 87.88%,84.85% and 51.52%,respectively.The comparison of brain blood flow perfusion image and brain glucose metabolism image with PWI showed that there were significant differences(P=0.001,0.004).The positive rate of the three methods were related to duration from onset of disease and the extent of injury of the affected blood vessel.Conclusion Brain glucose metabolism image and cerebral blood flow perfusion image are more sensitive in diagnosing TIA than PWI.