过敏性紫癜、湿疹、荨麻疹患者血清IgE对比分析 |
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引用本文: | 韩晨珠,陈丽莉,梁官钊,李保强.过敏性紫癜、湿疹、荨麻疹患者血清IgE对比分析[J].承德医学院学报,2015(3):205-207. |
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作者姓名: | 韩晨珠 陈丽莉 梁官钊 李保强 |
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作者单位: | 承德医学院附属医院皮肤科,河北承德,067000 |
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摘 要: | 目的::对比分析过敏性紫癜、湿疹、荨麻疹三种过敏性疾病患者血清中变应原特异性IgE和总IgE水平。方法:采用免疫印迹法检测341例过敏性疾病患者血清中总IgE和特异性IgE抗体水平。结果:过敏性紫癜、湿疹、荨麻疹患者总IgE阳性率分别为54.84%、65.79%、70.48%,以荨麻疹的阳性率最高。三种过敏性疾病吸入性变应原均以霉菌组合的阳性率最高;食入性变应原过敏性紫癜和湿疹牛奶的阳性率最高,荨麻疹以腰果类阳性率较高。结论:通过对三种过敏性疾病血清IgE的测定和对比分析,进一步证实Ⅰ型变态反应部分参与了过敏性紫癜和湿疹的致病;通过特异性变应原的测定,可了解引起患者过敏的变应原,为过敏性疾病的治疗和预防提供帮助。
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关 键 词: | 过敏性紫癜 湿疹 荨麻疹 总IgE 变应原特异性IgE |
COMPARATIVE ANALYSIS OF SERUM IGE IN PATIENTS WITH ANAPHYLACTOID PURPURA,ECZEMA AND URTICARIA |
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Institution: | HAN Chen-zhu;CHEN Li-li;LIANG Guan-zhao;Dermatological Department of Affiliated Hospital of Chengde Medical College; |
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Abstract: | Objective:To investigate the allergen-specific IgE and total IgE level in serum of patients with anaphylactoid purpura, eczema and urticaria.Methods: Immunoblotting was used to detect the allergen-speciifc IgE and total IgE level in serum of 341 cases allergic diseases patients.Results:The total IgE positive rate of anaphylactoid purpura, eczema and urticaria was respectively 54.84%, 65.79% and 70.48%; Among them, the positive rate of urticaria was the highest. For inhalant allergen, the positive rate of mold mixture was the highest in 3 allergic diseases. For food allergen, the positive rate of milk was the highest in anaphylactoid purpura and eczema; cashew allergies was the highest in urticaria. Conclusions:Comparative analysis of IgE level in serum of patients with 3 allergic diseases further conifrms that type I allergic reaction partly involves in allergic purpura and eczema. Determination of allergen can give a hand for treating and preventing allergic diseases. |
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Keywords: | Anaphylactoid purpura Eczema Urticaria Total IgE Allergen-speciifc IgE |
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