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肺结核患者T淋巴细胞亚群,红细胞免疫功能与核仁组成区 …
引用本文:王英年,刘瑞贞.肺结核患者T淋巴细胞亚群,红细胞免疫功能与核仁组成区 …[J].中华结核和呼吸杂志,1998,21(8):500-503.
作者姓名:王英年  刘瑞贞
作者单位:青岛纺织系统肺部疾病研究所,青岛市胸科医院
摘    要:目的 探讨结核病患者T淋巴细胞亚群,红细胞免疫功能及核仁组成相关嗜银蛋白(AgNORs)的关系及其临床意义。方法 采用碱性磷酸酶抗碱性磷酸酶(APAAP)法,红细胞花环试验以及AgNORs测定方法,对59例肺结核患者和50名正常对照组分别测定了外周血T淋巴细胞亚群,红细胞免疫C3b受体花环率(E-C3bRR)与红细胞循环免疫复合物花环率(E-ICR),AgNORs面积(GA),核面积(NA)及GA

关 键 词:肺结核  T细胞亚群  红细胞免疫功能  AgNOR染色

Significance and correlation of T lymphocyte subgroup, erythrocyte immune function and argyrophilic protein in nucleolar organizer regions in tuberculosis patients
T.Significance and correlation of T lymphocyte subgroup, erythrocyte immune function and argyrophilic protein in nucleolar organizer regions in tuberculosis patients[J].Chinese Journal of Tuberculosis and Respiratory Diseases,1998,21(8):500-503.
Authors:T
Institution:Lung Disease Institute, Qingdao Texile System, Qingdao 266042.
Abstract:OBJECTIVE: To study the significance and relationship of T lymphocyte subgroups, erythrocyte immune functions and argyrophilic protein in nucleolar organizer regions (AgNORs) in tuberculosis patients. METHOD: CD3+, CD4+, CD3+/CD4+ were determined using alkaline phosphatase-antialkaline phosphatase (APAAP) method, E-C3bRR and E-ICR were assayed by observing receptor rate. Granules area of AgNORs (GA) and nuclear area (NA) were studied by image analysis system. RESULT: CD3+, CD4+, CD4+/CD8+, E-C3bRR, GA/NA in tuberculosis patients were significantly lower than those in the healthy group (P < 0.001). However, the values of E-ICR, CD8+ were significantly higher than those of control group (P < 0.001). CONCLUSION: The results of T lymphocyte subgroup, erythrocyte functions and AgNORs are in accord, and might be usefull in assessing diagnosis and prognosis of tuberculosis.
Keywords:Tuberculosis  pulmonary    T lymphocyte subgroup    Erythrocyte    Nucleolus organizer region    Nuclear proteins
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