香蓝驱毒颗粒对扁平疣患者外周血T细胞亚群和IL-2的影响 |
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引用本文: | 封常霞,潘玉梅,李志玉.香蓝驱毒颗粒对扁平疣患者外周血T细胞亚群和IL-2的影响[J].中国麻风皮肤病杂志,2014(9):558-559. |
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作者姓名: | 封常霞 潘玉梅 李志玉 |
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作者单位: | 山东省潍坊市皮肤病防治所;山东省安丘市人民医院; |
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摘 要: | 目的:评价香蓝驱毒颗粒对扁平疣患者外周血T细胞亚群和IL-2的影响。方法:对120例扁平疣患者给予香蓝驱毒颗粒30 g,每日2次,治疗6周。检测治疗前后扁平疣患者外周血T细胞亚群及IL-2水平。结果:治疗前患者外周血CD4~+细胞数为32.25±1.83、CD4~+/CD8~+比值0.79±0.26及IL-2水平为2.24±0.68,治疗后上述3个参数分别为39.89±1.25、1.68±0.21和4.44±0.62,均显著升高(P0.01)。结论:香蓝驱毒颗粒能增强扁平疣患者的免疫功能及T细胞介导的免疫反应。
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关 键 词: | 扁平疣 香蓝驱毒颗粒 T淋巴细胞亚群 白细胞介素-2 |
Effects of Xianglan Qudu Keli on the levels of T lymphocyte subsets and IL-2 in peripheral blood of the patients with verruca plana |
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Institution: | FENG Chang-Xia, PAN Yu-mei, LI Zhi-yu. Weifang (Institute of Dermatology, Shandong, 261061) |
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Abstract: | Objective: To determine the influence of Xianglan Qudu Keli on the levels of T lymphocyte subsets and IL-2 in peripheral blood of the patients with varruca plana. Methods: One hundred and twenty patients with varruca plana were treated with Xianglan Qudu Keli, 30g twice a day for 6 weeks. T lymphocyte subsets and IL-2 level in peripheral blood of patients were detected before and after treatment. Results: Be-fore treatment, the CD4+ cell number was 32.25±1.83, the ratio of CD4+/CD8+ was 0.79±0.26 and the level of IL-2 was 2.24±0.68. After treatment, the CD4+cell number was 39.89±1.25, the ratio of CD4+/CD8+was 1.68±0.21 and the level of IL-2 was 4.44±0.62, which was significantly increased that those before treatment ( P〈0.01) . Conclusion:Xianglan Qudu Keli can enhance cellular immunity and T cell-mediated immune re-sponse in the patients with varruca plana. |
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Keywords: | varruca plana Xianglan Qudu Keli T lymphocyte subsets IL-2 |
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