甲真菌病400例致病真菌分析

目的:确定上海地区甲真菌病的致病菌种。方法:对本院皮肤科门诊就诊的直接镜检阳性的400例甲真菌病患者的甲标本做真菌分离培养和分析。结果:分离出致病真菌233株,其中皮肤癣菌120株(红色毛癣菌104株,须癣毛癣菌10株,犬小孢子菌3株,絮状表皮癣菌3株),酵母菌68株,非皮肤癣菌11株(曲霉6株,青霉5株),其余为丝状真菌。结论:上海地区甲真菌病的致病真菌以皮肤癣菌为主,酵母菌中非白念珠菌占有一定比例。

Analysis of pathogenic fungal strains in 400 patients of onychomycosis

Objective：To determine the pathogenic fungal strains isolated from onychomycosis in Shanghai. Methods：Fungal culture was performed on 400 patients of onychomycosis with positive results by direct microscopic examination. Results：A total of 233 strains of fungi was isolated,of which 120 strains were derma-tophytes （ Trichophyton rubrum in 104 isolates, Trichophyton mentagrophytes in 10, Microsporum canis in 3 and Epidermophyton floccosum in 3）, 68 were Saccharomycetes, 11 were non-dermatophytes （ Aspergillus 6 and Mould 5） and the rest were filamentous fungi. Conclusion：In Shanghai,the dominated pathogenic fungus of onychomycosis is Trichophyton rubrum, and the non-Candida albicans accounts for a proportion of the yeast.