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炮制对藏药南寒水石钙溶出率的影响
引用本文:全正香,杜玉枝,魏立新,肖远灿,杨红霞,李岑. 炮制对藏药南寒水石钙溶出率的影响[J]. 中国实验方剂学杂志, 2011, 17(11): 16-18
作者姓名:全正香  杜玉枝  魏立新  肖远灿  杨红霞  李岑
作者单位:1. 中国科学院西北高原生物研究所,西宁,810008;青海省藏药药理学与安全性评价研究重点实验室,西宁,810008;中国科学院研究生院,北京,100039
2. 中国科学院西北高原生物研究所,西宁,810008;青海省藏药药理学与安全性评价研究重点实验室,西宁,810008
基金项目:"重大新药创制"科技重大专项
摘    要:目的:通过测定各产地藏药南寒水石不同炮制品钙溶出率,揭示炮制对南寒水石钙溶出率的影响。方法:运用EDTA滴定法测定青海、西藏、甘肃、四川四省区产地藏药南寒水石生品、水淬品、酒淬品、酸酪淬品水煎液钙溶出率。结果:各种炮制方法均能显著提高藏药南寒水石水煎液钙溶出率,除黄南浪加和甘南合作美其乡的样品外,其余各产地南寒水石炮制品水煎液钙溶出率大小顺序均为酸酪淬品>酒淬品>水淬品。结论:通过测定和比较各产地藏药南寒水石不同炮制品的钙溶出率,为评价各产地南寒水石的品质、阐明南寒水石炮制机理和规范其炮制工艺提供了基础数据。

关 键 词:矿物药  南寒水石  溶出率    炮制
收稿时间:2011-02-18

Impact of Processing on Dissolution Rate of Calcium of Traditional Tibetan Medicine Nanhanshuishi
QUAN Zheng-xiang,DU Yu-zhi,WEI Li-xin,XIAO Yuan-can,YANG Hong-xia and LI Cen. Impact of Processing on Dissolution Rate of Calcium of Traditional Tibetan Medicine Nanhanshuishi[J]. China Journal of Experimental Traditional Medical Formulae, 2011, 17(11): 16-18
Authors:QUAN Zheng-xiang  DU Yu-zhi  WEI Li-xin  XIAO Yuan-can  YANG Hong-xia  LI Cen
Affiliation:Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Xining 810008, China; Graduate University of Chinese Academy of Sciences, Beijing 100039, China;Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Xining 810008, China;Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Xining 810008, China;Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Xining 810008, China;Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Xining 810008, China; Graduate University of Chinese Academy of Sciences, Beijing 100039, China;Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China; Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Xining 810008, China; Graduate University of Chinese Academy of Sciences, Beijing 100039, China
Abstract:Objective: To reveal the impact of process on dissolution rate of calcium of traditional Tibetan medicine Nanhanshuishi by determining various processed Nanhanshuishi decoctions. Method: The calcium content in various Nanhanshuishi (crude, water quenched, liquor quenched,and yoghurt quenched) was determined by EDTA titration. Result: The dissolution rate of calcium of traditional Tibetan medicine Nanhanshuishi was raised after being processed, the order of dissolution rate of calcium of processed Nanhanshuishi was the yoghurt quenched>the liquor quenched>the water quenched. Conclusion: The study has provided basis for evaluating quality, clarifying the processing mechanism and regulating the processing technology of traditional Tibetan medicine Nanhanshuishi.
Keywords:mineral medicine  Nanhanshuishi  dissolution rate  calcium  processing
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