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杀虫净的毒性研究—人的日容许摄入量建议值
引用本文:陈润涛 张杏坤. 杀虫净的毒性研究—人的日容许摄入量建议值[J]. 中国职业医学, 1993, 20(6): 360-362
作者姓名:陈润涛 张杏坤
作者单位:广东省职业病防治院,广东省职业病防治院,广东省职业病防治院,广东省职业病防治院,广东省职业病防治院 广州市怡乐路 510260,广州市怡乐路 510260,广州市怡乐路 510260,广州市怡乐路 510260,广州市怡乐路 510260
摘    要:本文对杀虫净进行了大鼠急性经口毒性、小鼠骨髓微核试验和大鼠90天喂饲试验。杀虫净经口LD50为96.31mg/kg,属中等毒农药,对小鼠骨髓嗜多染红细胞微核无明显影响。大鼠90天喂饲试验结果表明,杀虫净剂量为0.1mg/kg时,大鼠的生长发育、血液生化及病理组织学指标均未见不良改变,大鼠最大无作用剂量为0.1mg/kg,人的日容许摄入量建议植为0.001mg/kg。

关 键 词:杀虫净 毒性 致突变 日容许摄入量

Research on the toxicity of shachongjing (SCJ)
Chen Runtao. Research on the toxicity of shachongjing (SCJ)[J]. China Occupational Medicine, 1993, 20(6): 360-362
Authors:Chen Runtao
Affiliation:Chen Runtao
Abstract:The toxic effect of SCJ including acute toxicity (rats), bone marrow MCN (mice) and a 90-day feeding test (rats) were studied. SCJ was classified as middle toxicity insectcide, with oral LD_(50) 96.31 mg/kg. There was no obvious effect on the micronucleared red cells in mice bone marrow. The 90-day feedins test demonstrated that no abnormality was found in term of growth blood biochemical indices and histological structure when the dietary content of SCJ was kept under 0.1 mg/kg. The maximum non-observed effect level on rats was consequently 0.1 mg/kg, and the recommended ADI on human body would be 0.001 mg/kg.
Keywords:shachongjing  acute toxicity  maximum non-observed effect level
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