补肾养血法治疗狼疮肾炎环磷酰胺冲击疗法后引起的白细胞减少症临床研究

目的：观察补肾养血法治疗狼疮肾炎环磷酰胺冲击疗法后引起的白细胞减少症的临床疗效。方法：将30例患者随机分为治疗组16例与对照组14例,治疗组给予补肾养血中药治疗,对照组口服利可君、维生素B4片、肌苷片,两组均以14 d为1疗程。结果：治疗组有效率93.7%,对照组有效率71.0%,治疗组疗效明显优于对照组（P〈0.01）。结论：补肾养血中药治疗狼疮肾炎环磷酰胺冲击疗法后引起的白细胞减少症有较好的临床疗效。

Clinical Study on the Reinforcing Kidney and Nourishing Blood Method in Treating Leukopenia Caused by Cyclophosphamide Pulse Therapy for Lupus Nephritis

Objective：To observe the clinical effects of reinforcing kidney and nourishing blood method in treating leukopenia caused by cyclophosphamide pulse therapy for lupus nephritis.Methods：30 cases of lupus nephritis were randomly divided into treatment group with 16 cases and control group with 14 cases.The treatment group was treated with kidney reinforcing and blood nourishing herbs and the control group was treated with Leucogen,Vitamin B4 tablets and inosine tablets.Both groups were treated for two weeks as a course of treatment.Results：The total effective rate of the treatment group was 93.7% and that of the control group was 71%,so the curative effect of the treatment group was superior to that of the control group（P〈0.01）.Conclusion：Kidney reinforcing and blood nourishing herbs have excellent therapeutic effect in treating leukopenia caused by cyclophosphamide pulse therapy for lupus nephritis.