| 温氧合血心停搏液连续灌注对离体兔心肌的保护作用 |
| |
| 引用本文： | 廖永德,张本固,赵金平,张良华,陈夏丰.温氧合血心停搏液连续灌注对离体兔心肌的保护作用[J].华中科技大学学报(医学版),1997(5). |
| |
| 作者姓名： | 廖永德 张本固 赵金平 张良华 陈夏丰 |
| |
| 作者单位： | 同济医科大学附属同济医院外科!武汉，430030，同济医科大学附属同济医院外科!武汉，430030，同济医科大学附属同济医院外科!武汉，430030，同济医科大学附属同济医院外科!武汉，430030，同济医科大学附属同济医院外科!武汉，430030 |
| |
| 摘 要： | 实验采用离体工作状态兔心模型，比较研究温氧合血心停搏液连续灌注与低温冷晶体心停搏液间断灌注对心肌的保护作用。结果表明，温氧合血心停搏液能为停搏心肌提供氧与基质，保存和增加心肌能量储备，避免缺血／再灌注损伤，保持心肌组织结构完整，使复苏后心功能迅速恢复至停搏前水平，心肌保护效果明显优于冷晶体心停搏液间断灌注。
|
| 关 键 词： | 温氧合血心停搏液 冷晶体心停搏液 心肌再灌流损伤 心肌 |
The Myocardial Protection by Continuous Perfusion of Warm Oxygenated Blood Cardioplegic Solution in Isolated Working Rabbit Hearts |
| |
| Liao Yongde,Zhang Bengu, Zhao Jinping et al.The Myocardial Protection by Continuous Perfusion of Warm Oxygenated Blood Cardioplegic Solution in Isolated Working Rabbit Hearts[J].Journal of Huazhong University of Science and Technology(Health Sciences),1997(5). |
| |
| Authors: | Liao Yongde Zhang Bengu Zhao Jinping |
| |
| Abstract: | The myocardial protection by continuous perfusion of warm oxygenated blood cardioplegic solution and by intermittent perfusion of cold crystalloid cardioplegic solution in isolated working rabbit hearts were studied in this experiment. The results showed that the warm oxygenated blood cardioplegic solution could provide the arrest myocardial cells with oxygen and substrates, preserve and increase the energy reserve in the myocardial cells, prevent the myocardial cells from ischemic/reperfusion injury, keep the myocardial cell ultrastructure intact, and help the cardiac function recover rapidly to the pre-arrest level. We come to the conclusion that the myocardial protection by continuous perfusion of warm oxygenated blood cardioplegic solution is more effective than by intermittent perfusion of cold crystalloid cardioplegic solution. |
| |
| Keywords: | warm oxygenated blood cardioplegic solution cold crystalloid cardioplegic solution myocardial ischemic/reperfusion injury myocardium |
| 本文献已被 CNKI 等数据库收录！ |
