| 心力衰竭患者血浆肾素活性和血管紧张素Ⅱ浓度变化及其与钠的关系 |
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| 引用本文： | 赵连友,张宁仔.心力衰竭患者血浆肾素活性和血管紧张素Ⅱ浓度变化及其与钠的关系[J].第四军医大学学报,1988(6). |
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| 作者姓名： | 赵连友 张宁仔 |
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| 作者单位： | 唐都医院心血管内科
(赵连友)，唐都医院心血管内科(张宁仔) |
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| 摘 要： | 作者报告不同类型心衰患者血浆中PRA、ATⅡ、血清钠和24h尿钠排出量,并探讨钠对心衰患者PRA和ATⅡ浓度的影响。结果表明:①左心衰患者PRA和ATⅡ浓度高于健康人和右心衰患者;②左心衰患者属高肾素型,右心衰患者属低肾素型或正常肾素型;③心衰患者PRA和ATⅡ浓度与尿钠排出量呈负相关。我们认为按肾素活性或钠指数对心衰分型,有利于选择治疗心衰的药物。
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| 关 键 词： | 心力衰竭 充血性 肾素 血管紧张素Ⅱ 钠 |
Changes of Plasma Renin Activity and Angiotensin II Levels Heart Failure Patients and Their Relationship to Sodium |
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| Zhao Lianyou and Zhang Ningzi.Changes of Plasma Renin Activity and Angiotensin II Levels Heart Failure Patients and Their Relationship to Sodium[J].Journal of the Fourth Military Medical University,1988(6). |
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| Authors: | Zhao Lianyou and Zhang Ningzi |
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| Institution: | Zhao Lianyou and Zhang NingziDepartment of Cardicvascular diseases,Tangdu Hospital |
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| Abstract: | The plasma PRA, ATII, serum sodium and the volume of urinary sodium excretion within 24 hours were determined in 20 cases of heart failure, in order to investigate the effect of sodium on the PRA and ATII levels. It was found that (1) the PRA and AT I levels of left heart failure patients were higher than those of normal persons and right heart failure patients, but serum sodium and urinary sodium excretion of the left heart failure patients were lower than normal persons and right heart failure patients; (2) the left heart failure patients were of high renin activity type and the right heart failure patients of low or normal types; and (3) in heart failure patients, PRA, AT II level and the volume of urinary sodium excretion are of negative correlation. The authors suggest that it may be useful for the choice of drugs in the treatment of heart failure if we divide the heart failure patients into subgroups by PRA and sodium index. |
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